Anti-Mullerian Hormone: A Potential Marker for Recruited Non-Growing Follicles of Ovarian Pool in Women with Polycystic Ovarian Syndrome
January 2013
in “
Journal of Clinical and Diagnostic Research
”
Studysummary This study found that anti-mullerian hormone levels are significantly elevated in infertile women with polycystic ovarian syndrome compared to those with regular cycles, suggesting it as a potential marker for diagnosing PCOS-related infertility.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
In the 2013 study involving 120 infertile women, researchers found that Anti-Mullerian Hormone (AMH) levels were significantly higher in the 60 women with Polycystic Ovarian Syndrome (PCOS) than in the 60 controls with regular cycles. The study determined that AMH could be used as a marker for recruited non-growing follicles in the ovaries of women with PCOS. With a cut-off point of 3.34 ng/ml for AMH, the diagnostic accuracy was high, with a sensitivity of 98%, specificity of 93%, Positive Predictive Value (PPV) of 93%, and Negative Predictive Value (NPV) of 98%. These findings suggest that AMH is a reliable diagnostic tool for PCOS and reflects the number of small follicles, indicating the severity of follicular arrest in PCOS patients.
