Anti-Mullerian Hormone: A Potential Marker for Recruited Non-Growing Follicles of Ovarian Pool in Women with Polycystic Ovarian Syndrome

    January 2013 in “ Journal of Clinical and Diagnostic Research ”
    Saikumar P, Vs Kalai Selvi, Prabhu K, P. C. Venkatesh, Prashanth Krishna
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    TLDR AMH levels are higher in women with PCOS and can indicate the number of small follicles in their ovaries.
    In the 2013 study involving 120 infertile women, researchers found that Anti-Mullerian Hormone (AMH) levels were significantly higher in the 60 women with Polycystic Ovarian Syndrome (PCOS) than in the 60 controls with regular cycles. The study determined that AMH could be used as a marker for recruited non-growing follicles in the ovaries of women with PCOS. With a cut-off point of 3.34 ng/ml for AMH, the diagnostic accuracy was high, with a sensitivity of 98%, specificity of 93%, Positive Predictive Value (PPV) of 93%, and Negative Predictive Value (NPV) of 98%. These findings suggest that AMH is a reliable diagnostic tool for PCOS and reflects the number of small follicles, indicating the severity of follicular arrest in PCOS patients.
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