Helicobacter Pylori Infection and Polycystic Ovary Syndrome in Adolescent and Young Adult Patients

The study examined the potential association between Helicobacter pylori infection and polycystic ovary syndrome (PCOS) in 167 adolescent and young adult females, of which 86 had PCOS and 81 were age-matched controls. The average age of the participants was 18.57 ± 2.40 years. PCOS diagnosis followed the Amsterdam ESHRE/ASRM guidelines, and H. pylori IgG levels were measured using ELISA. Results showed no significant link between the presence of H. pylori IgG and PCOS (P = 0.924), nor with white blood cell count or C-reactive protein (P = 0.064; P = 0.383, respectively). The study concluded that H. pylori prevalence did not differ based on PCOS status in this demographic, suggesting that further research is needed to explore any possible connection between H. pylori and PCOS.