TLDR H. pylori infection is not linked to PCOS or infertility.
The 2015 study involved 254 participants, 127 with Polycystic Ovary Syndrome (PCOS) and 127 without. The research aimed to compare the levels of Helicobacter pylori specific antibodies (IgA, IgG, and anti-CagA) in both groups. The results showed that 62% of the PCOS group and 60% of the non-PCOS group had increased levels of IgG antibodies to H. pylori. The overall seroprevalence of positive anti-CagA IgG antibodies was 60.5% in PCOS women and 39.5% in non-PCOS women. However, there was no significant difference in the prevalence of H. pylori specific antibodies between the two groups. The study concluded that H. pylori infection probably did not affect infertility or reproduction, and high levels of H. pylori specific antibodies were not associated with PCOS.
926 citations,
June 2010 in “BMC Medicine” Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.
815 citations,
April 2010 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS should be screened for heart disease risk and manage their health to prevent it.
1 citations,
September 2016 in “Journal of Obstetrics and Gynaecology Research” The study found no significant link between Helicobacter pylori infection and polycystic ovary syndrome in young females.
7 citations,
January 2017 in “American Journal of Biological Anthropology” Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.
47 citations,
August 2014 in “The Journal of Clinical Endocrinology and Metabolism” The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.
1 citations,
July 2023 in “Frontiers in Immunology” Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
16 citations,
February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
