Serological Diagnosis of Helicobacter Pylori Infection in Patients With Polycystic Ovary Syndrome

The 2015 study involved 254 participants, 127 with Polycystic Ovary Syndrome (PCOS) and 127 without. The research aimed to compare the levels of Helicobacter pylori specific antibodies (IgA, IgG, and anti-CagA) in both groups. The results showed that 62% of the PCOS group and 60% of the non-PCOS group had increased levels of IgG antibodies to H. pylori. The overall seroprevalence of positive anti-CagA IgG antibodies was 60.5% in PCOS women and 39.5% in non-PCOS women. However, there was no significant difference in the prevalence of H. pylori specific antibodies between the two groups. The study concluded that H. pylori infection probably did not affect infertility or reproduction, and high levels of H. pylori specific antibodies were not associated with PCOS.