Association Between Chlamydia Trachomatis and Helicobacter Pylori With Inflammation in Polycystic Ovary Syndrome: A Cross-Sectional Study

    December 2024 in “ Medicina
    Yeşim Çağlar, Mine İslimye Taşkın
    This study investigated the association between Helicobacter pylori and Chlamydia trachomatis infections and inflammation in polycystic ovary syndrome (PCOS) by comparing 40 women with PCOS to 40 healthy controls. The results showed no significant association between PCOS and the presence of H. pylori or C. trachomatis antibodies. However, C-reactive protein (CRP) levels, an inflammation marker, were significantly higher in the PCOS group. Additionally, diabetes mellitus was more common in the PCOS group, while the control group had a higher smoking rate. Other factors such as BMI, LH, HOMA-IR, TSH, and TG levels were elevated in PCOS patients, while FSH was lower. The study concludes that while PCOS is associated with chronic low-grade inflammation, the role of infections like H. pylori and C. trachomatis in its etiology remains unclear, suggesting further research into microbiota and periodontal diseases in PCOS.
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