Association Between Chlamydia Trachomatis and Helicobacter Pylori With Inflammation in Polycystic Ovary Syndrome: A Cross-Sectional Study

    December 2024 in “ Medicina
    Yeşim Çağlar, Mine İslimye Taşkın
    TLDR PCOS is linked to chronic low-grade inflammation, but the role of certain infections is unclear.
    This study examined the link between Helicobacter pylori and Chlamydia trachomatis infections and inflammation in 40 women with polycystic ovary syndrome (PCOS) compared to 40 healthy controls. The findings revealed no significant association between PCOS and the presence of H. pylori or C. trachomatis antibodies. However, CRP levels, an inflammation marker, were notably higher in the PCOS group, indicating chronic low-grade inflammation. The study suggests that this inflammation in PCOS may be more related to factors like increased visceral adipose tissue and insulin resistance rather than these infections, highlighting the need for further research into the role of microbiota and periodontal diseases in PCOS.
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