The Difficulty of Finding Healthy Volunteers

    January 1993 in “ Journal of Dermatological Treatment ”
    Valerie Walkden, J. D. Wilkinson
    Image of study
    TLDR Most people who volunteered for a health study had medical issues, showing the need for careful screening before trials.
    In 1993, a study involving 370 individuals seeking to participate in alopecia treatment programs found that a high percentage of these ostensibly healthy volunteers had medical abnormalities. Specifically, 69% had abnormal blood test results, 30% had abnormal ECGs, and 26% had diastolic blood pressure of 85 mmHg or higher. Overall, 66% had some form of abnormality detected through testing. The study concluded that it is crucial to have pretreatment testing to ensure that any abnormalities are not wrongly attributed to the drug being tested. This research underscored the difficulties in establishing 'normal' baseline values for control subjects in clinical trials and the associated costs of thorough screening.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 2 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

    Similar Research

    5 / 1000+ results