research Evaluation of Oxidative Stress Markers in Androgenetic Alopecia Patients
AGEs and their receptors play a significant role in hair loss by causing inflammation and oxidative stress.
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90-120 / 938 results research Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities
The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
research Dynamic Evaluation of Pathological Changes in a Mouse Acne Model by Optical Imaging Technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant did not significantly improve hair growth in men with hair loss.
research Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach
The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
research What Is the Male Polycystic Ovary Syndrome Phenotype?
Men can have genetic risks for PCOS-related traits like obesity and diabetes.
research Polycystic Ovary Syndrome (PCOS) – An Overview
PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure
Changing disulfide bonds in human hair affects its melting behavior and thermal stability.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
research Incidence of Hair Loss Concerns in Women Who Wear the Hijab: An Exploratory Survey
Many Hijabi women worry about hair loss, but fewer actually experience it.
research Type D Personality, Stress Levels, and Coping Strategies in Women with Androgenetic Alopecia and Polycystic Ovary Syndrome
Women with type D personality and PCOS experience more stress and use less effective coping strategies.
research Methylenetetrahydrofolate Reductase C677T Mutation in Patients with Alopecia Areata in Turkish Population
The MTHFR C677T mutation may increase the risk of alopecia areata in the Turkish population.
research Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells
Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
research Pregnancy and the Hair Growth Cycle: Anagen Induction Against Hair Growth Disruption Using Nourkrin with Marilex, a Proteoglycan Replacement Therapy
Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.
research Dermatological Problems and COVID-19
COVID-19 can cause skin problems and affect dermatology treatments, with recommendations for skin care and cautious use of certain drugs.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Healthcare Innovation and Patent Law’s Pharmaceutical Privilege: Is There a Pharmaceutical Privilege? And If So, Should We Remove It?
The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.
research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing
Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.
research Regulation and Dysregulation of Hair Regeneration: Aiming for Clinical Application
Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
research Public Awareness of the Symptoms and Risk Factors of Thyroid Disease in Saudi Arabia
Many people in Saudi Arabia lack awareness of thyroid disease risk factors and symptoms, highlighting the need for better health education.
research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research MicroRNAs in the Pathogenesis of Male Pattern Baldness
Different levels of microRNAs in different parts of the scalp can cause male pattern baldness.
research Overexpression of Cyclooxygenase-2 in the Skin of Adult Transgenic Mice Leads to Sebaceous Gland Hyperplasia and Thinning of Hair Shafts
Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.
research Special Collection on Inward Rectifying Potassium Channels
Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research A Comprehensive Literature Review of JAK Inhibitors in the Treatment of Alopecia Areata
JAK inhibitors show promise in effectively treating hair loss from alopecia areata.
research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Tissue and Circulating MicroRNA Co-expression Analysis Shows Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia
Certain microRNAs might help identify and understand Frontal Fibrosing Alopecia.
research Dermatologic Manifestations of Endocrine Disorders
Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.