Special Collection on Inward Rectifying Potassium Channels

    January 2023 in “ American journal of physiology. Cell physiology ”
    Jerod S. Denton, Eric Delpire
    Image of study
    TLDR Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
    The document reviews the current research on inward rectifier potassium (Kir) channels, which are crucial in various cellular, tissue, and organ processes. The Kir channel family, consisting of 16 genes (KCNJx), is expressed in a cell-type-specific manner in both excitable and nonexcitable cells. These channels are implicated in diseases like Cantu syndrome, characterized by excessive hair growth and other disorders, and can be targeted by drugs like glibenclamide. They also play roles in lymphatic vessel function, insulin secretion, kidney function, nervous system function, and vision. The review emphasizes the need for more research and the therapeutic potential of Kir channels in various diseases.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 14 results

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 11 months ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community M 20 | 5M Fin / 2.5M Min | Progress

      in Progress Pictures  48 upvotes 1 year ago
      A user's successful hair loss treatment using ketoconazole shampoo, 0.5mg finasteride, and 5% liquid minoxidil. They noticed significant results after 4 months, with reduced hair fall observed earlier.

      community My experience with 1mg fin eod

      in Finasteride/Dutasteride  18 upvotes 1 year ago
      A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.

      community 4 months update (fin + min + derma stamps)

      in Progress Pictures  644 upvotes 2 months ago
      The user shared a 4-month update on hair loss treatment using finasteride, minoxidil, and derma stamps, showing significant progress. The user experienced no side effects and plans to continue the treatment, updating monthly.

      community 16 months finasteride & minoxidil progress

      in Progress Pictures  605 upvotes 5 months ago
      User shared 16-month progress using finasteride 1 mg/day and minoxidil 5% solution once/day, noting significant regrowth, especially in temporal peaks. Users discussed shedding, side effects, and positive feedback from others.

    Similar Research

    5 / 250 results