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The Role of ATP-Sensitive Inward Rectifier Potassium Channels in the Regulation of Reactive Oxygen Species in the Western Honey Bee, Apis Mellifera L.

research The Role of ATP-Sensitive Inward Rectifier Potassium Channels in the Regulation of Reactive Oxygen Species in the Western Honey Bee, Apis Mellifera L.

June 2022

Activating certain potassium channels in honey bees can lower antioxidant levels and reduce death rates during heavy mite infestations, potentially aiding their immune response.

research Special Collection on Inward Rectifying Potassium Channels

3 citations, January 2023 in “American journal of physiology. Cell physiology”

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

research The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels

5 citations, September 2022 in “Molecular pharmacology”

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

5 citations, January 2018

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

1 citations, August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

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community If RU58841 is such an effective anti androgen

in Research/Science 48 upvotes 10 months ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community M 20 | 5M Fin / 2.5M Min | Progress

in Progress Pictures 48 upvotes 1 year ago

A user's successful hair loss treatment using ketoconazole shampoo, 0.5mg finasteride, and 5% liquid minoxidil. They noticed significant results after 4 months, with reduced hair fall observed earlier.

community My experience with 1mg fin eod

in Finasteride/Dutasteride 22 upvotes 1 year ago

A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.

community 4 months update (fin + min + derma stamps)

in Progress Pictures 639 upvotes 1 month ago

The user shared a 4-month update on hair loss treatment using finasteride, minoxidil, and derma stamps, showing significant progress. The user experienced no side effects and plans to continue the treatment, updating monthly.

community 16 months finasteride & minoxidil progress

in Progress Pictures 608 upvotes 4 months ago

User shared 16-month progress using finasteride 1 mg/day and minoxidil 5% solution once/day, noting significant regrowth, especially in temporal peaks. Users discussed shedding, side effects, and positive feedback from others.

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