This study observed that depression and anxiety notably affect quality of life for patients with systemic lupus erythematosus, especially among African-American and Hispanic individuals who report higher unmet psychological needs.
November 2023 in “International Journal of Trichology” This case report describes a 19-year-old male with systemic lupus erythematosus presenting with an unusual combination of mucinous nonscarring alopecia and papulonodular mucinosis, noted by mucin deposition in skin lesions, which responded partially to treatment with hydroxychloroquine and prednisolone.
In this report, a 51-year-old woman with systemic lupus erythematosus presented with recurrent joint pain and irregular patches of hair loss, raising differential diagnoses of androgenetic alopecia, lupus-related alopecia, or seborrheic dermatitis.
In this case report, a patient's atypical neuropsychiatric and dermatological symptoms were crucial for diagnosing systemic lupus erythematosus, highlighting the disease's clinical heterogeneity and the importance of early detection to prevent organ damage.
October 2023 in “F1000Research” This case report describes a 21-year-old woman with systemic lupus erythematosus who developed tuberculous lymphadenitis, highlighting the increased risk of TB in patients on long-term immunosuppressive therapy.
October 2023 in “CHEST Journal” This case report illustrates that diffuse alveolar hemorrhage can be a serious initial manifestation of systemic lupus erythematosus, characterized by progressive dyspnea, hemoglobin decrease, and respiratory symptoms.
September 2023 in “Food and chemical toxicology” In this study on Sprague-Dawley rats, 0.60 mg/kg doses of L-Se-methylselenocysteine and sodium selenite were associated with liver toxicity and reduced sperm motility, while Se-enriched peptides showed no observable adverse effects up to 0.60 mg/kg.
September 2023 in “Cureus” This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.
September 2023 in “Journal of the American Academy of Dermatology” Methylprednisolone treatment helps most alopecia areata patients, but young age, extensive hair loss, and low vitamin D can affect results.
In this study conducted at an Egyptian outpatient clinic, researchers found that systemic lupus erythematosus patients who were non-adherent to medication had a higher rate of hospitalization and more clinical symptoms compared to those who adhered to their prescribed treatments.
August 2023 in “The American Journal of Medicine” This case report describes a 17-year-old female patient diagnosed with systemic lupus erythematosus, presenting with arthralgia, hair loss, and Raynaud's phenomenon. The diagnosis was supported by elevated ESR and positive autoantibodies, and treatment included hydroxychloroquine and prednisone.
August 2023 in “JAAD Case Reports” This report describes a 57-year-old woman with fibrosing alopecia in a pattern distribution, who experienced hair regrowth with combined treatment including hydroxychloroquine and other topical and oral therapies.
August 2023 in “Rheumatology” In this case report, researchers describe a 17-year-old African male with an overlapping condition of juvenile dermatomyositis and systemic scleroderma, highlighting the importance of thorough history-taking and physical examination for accurate diagnosis and suggesting early referral to a pediatric rheumatologist to prevent severe outcomes.
July 2023 in “Annals of African Medicine” This case report describes a 24-year-old female with systemic lupus erythematosus and aggressive periodontitis, showing satisfactory outcomes after treatment with nonsurgical periodontal therapy and xenograft over an 8-year follow-up.
This study suggests that the EULAR/ACR classification criteria for SLE may help predict organ damage, particularly in renal, cardiovascular, dermatological, and gonadal domains.
In this study involving 30 Kazakh women with systemic lupus erythematosus, the researchers found a strong correlation between disease activity (SELENA-SLEDAI scores) and organ damage (SLICC/ACR scores), which depended on disease duration and reliably reflected cumulative disease activity.
In this study, Korean patients with systemic lupus erythematosus had a worse perception of the COVID-19 vaccine compared to the influenza vaccine, with higher reported adverse events and concerns about causing lupus flares.
In this case report, a 19-year-old woman with systemic lupus erythematosus experienced significant improvement in neuropsychiatric symptoms, including psychosis and seizures, following treatment with high-dose corticosteroids, immunosuppressants, and antidepressants.
This case report highlights that Tjalma Syndrome may present as a main symptom of systemic lupus erythematosus and should be considered in patients with ascites, pleural effusions, and elevated CA-125 levels.
June 2023 in “F1000Research” This case report describes a 21-year-old female with systemic lupus erythematosus who developed tuberculous lymphadenitis, which was attributed to her compromised immune system from long-term immunosuppressive therapy.
In this retrospective cohort study of individuals diagnosed with late-onset systemic lupus erythematosus after age 80, most were women, joint and skin issues were prevalent, average survival was 4.5 years, and men had notably lower survival rates with higher mortality.
May 2023 in “Elsevier eBooks” This study reports that while systemic immunotherapies are often used for immune-mediated hair loss, they may also be considered for treating androgenetic alopecia when it coexists with immune-related conditions like alopecia areata.
April 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This case study reported significant improvement in autoimmune-related symptoms, including complete hair regrowth, in a patient with systemic lupus erythematosus and alopecia areata after treatment with the LGS Protocol.
March 2023 in “Revista română de reumatologie” This article reviews the classification and treatment of cutaneous manifestations in systemic lupus erythematosus, highlighting the importance of monitoring for disease progression and reports no new clinical results.
This case report details a 38-year-old woman in Sri Lanka diagnosed with systemic lupus erythematosus-associated protein-losing enteropathy, identified through hypoalbuminemia and EULAR criteria in a resource-limited setting.
March 2023 in “Authorea (Authorea)” This case report describes a 5-year-old Sudanese boy with systemic-onset juvenile idiopathic arthritis who also exhibited unique cutaneous manifestations and peripheral eosinophilia alongside tinea capitis.
March 2023 in “Journal of Pakistan Society of Internal Medicine.” This case report highlights a young woman diagnosed with lupus enteritis, illustrating the importance of early diagnosis and treatment in this rare clinical manifestation of systemic lupus erythematosus.
March 2023 in “Journal of Pakistan Association of Dermatologists” This case report highlights that rosacea can be misdiagnosed as systemic lupus erythematosus, with symptom improvement seen after switching from long-term corticosteroid use to topical metronidazole, nicotinamide, and tretinoin.
March 2023 in “International Journal of Dermatology” This case report identifies a 51-year-old woman whose nonpruritic urticated rash was an initial presentation of systemic lupus erythematosus, highlighting the importance of comprehensive serological evaluation and biopsy for accurate diagnosis.
March 2023 in “Nigerian Journal of Clinical Practice” This study found that SLE patients with hair loss exhibited significant differences in the size and number of sebaceous glands compared to those without hair loss, but showed no histopathological differences between affected and unaffected scalp areas.