LP-161 Tjalma Syndrome (Pseudo-Pseudo Meigs Syndrome): Polyserositis With Increased CA-125 in Patients With Systemic Lupus Erythematosus

Tjalma Syndrome, also known as Pseudo-Pseudo Meigs Syndrome, is a rare condition associated with systemic lupus erythematosus (SLE), characterized by massive ascites, pleural effusions, and elevated CA-125 levels, without the presence of benign or malignant tumors. The document describes a case of a 31-year-old woman with SLE who presented with these symptoms and was diagnosed with Tjalma Syndrome after thorough examinations ruled out tuberculosis and malignancy. Her treatment included high-dose methylprednisolone, mycophenolic acid, hydroxychloroquine, ramipril, furosemide, calcium carbonate, and therapeutic ascites puncture, leading to her discharge in improved condition. The case emphasizes the importance of considering Tjalma Syndrome in the differential diagnosis for SLE patients with ascites, pleural effusions, and increased CA-125, to ensure proper management and avoid unnecessary surgical procedures.