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      learn Platelet-Rich Plasma

      growth factors taken from your blood and injected into your scalp to stimulate hair

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 month ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community I can't take care of myself because of hair loss.

      in Chat  163 upvotes 3 months ago
      The conversation is about a user feeling hopeless due to hair loss despite using finasteride, dutasteride, and OM for over a year. Responses suggest therapy, self-improvement, and changing perspectives on appearance.