Skin Diseases Due to Endocrine Alterations
January 2006
in “
The Aging Male
”
androgenetic alopecia testosterone estrogen thyroid hormones acanthosis nigricans Addison's disease diabetic dermopathy diabetic foot ulcers Carney complex POEMS syndrome glucagonoma syndrome vitamin D vitiligo melanocytes male pattern baldness female hormones skin darkening adrenal insufficiency diabetic skin condition diabetic foot condition rare endocrine disorder skin depigmentation skin pigment cells
TLDR Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
The document reviewed the link between endocrine disorders and various skin diseases, particularly in the elderly. It highlighted that skin changes could be indicative of underlying endocrine diseases. Conditions such as acanthosis nigricans, androgenetic alopecia, and Addison's disease were discussed, with their pathophysiology, clinical presentation, and treatment options. The review also covered the effects of hormones like testosterone, estrogen, and thyroid hormones on the skin, and the importance of these hormones in maintaining skin health. It mentioned the prevalence of diabetic dermopathy in diabetic patients and the serious complications of diabetic foot ulcers. Additionally, the document discussed rare conditions like Carney complex, POEMS syndrome, and glucagonoma syndrome, emphasizing the need for understanding the endocrine basis for proper diagnosis and treatment. It also touched on the role of vitamin D in skin health and the challenges in treating vitiligo, suggesting that further understanding of immune reactions affecting melanocytes could lead to new therapeutic strategies.
