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research Full‐house nephropathy in antinuclear antibody‐negative systemic lupus erythematosus: A case report
In this case study, a 25-year-old presented with symptoms of lupus but tested negative for antinuclear antibodies, complicating diagnosis. The researchers emphasize that comprehensive diagnostic approaches, beyond ANA testing, are vital for effectively identifying and treating lupus nephritis to avoid serious outcomes.
research 008 Stratifying alopecia areata systemic treatments: Tailored approaches to disease severity
Tailored treatments for alopecia areata show promising results, with pulse steroids effective for mild cases and Ritlecitinib, Dupilumab, or methotrexate and prednisone effective for severe cases.
research LB1007 Systemic treatment with a KLK5 inhibitor shows efficacy in a murine model of Netherton syndrome
This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.
research Dermatological Presentations in Systemic Lupus Erythematosus: A Comprehensive Case Study
This case report describes a 27-year-old female diagnosed with subacute cutaneous lupus erythematosus, who experienced improvement in symptoms following treatment, including fading of skin lesions.
research Good efficacy achieved by telitacicept in treatment of systemic lupus erythematosus with alopecia areata
Telitacicept effectively improved hair regrowth in a woman with lupus and alopecia.
research Anifrolumab treatment improves patient-reported quality of life and decreases disease activity and corticosteroid use in patients with systemic lupus erythematosus: A qualitative study in Denmark
This study provides insights into systemic lupus erythematosus patients' experiences with Anifrolumab, highlighting improvements in symptoms and health-related quality of life, despite ongoing daily life impacts.
research AB0987 ANIFROLUMAB TREATMENT IMPROVES QUALITY OF LIFE AND DECREASES SYSTEMIC CORTICOSTEROID USE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
This study explored the experiences of systemic lupus erythematosus patients receiving Anifrolumab, revealing improvements in self-reported symptoms and daily life impacts alongside decreased disease activity and lowered corticosteroid use.
research AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS
This pilot study found that a high fat lard diet may protect against fibrosis and affect the hair follicle cycle in a mouse model of systemic sclerosis, unlike a high fat coconut oil diet.
research POS0548 ACUTE AND SUBACUTE SKIN MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS ARE ASSOCIATED WITH AN EARLIER RESPONSE TO BELIMUMAB THAN THE CHRONIC PHENOTYPE: PRELIMINARY DATA FROM THE NEW NATION-WIDE COHORT OF BELIMUMAB IN REAL LIFE SETTING STUDY—NEW JOINT AND SKIN (BERLISS-NEJS)
In this multicenter study, belimumab effectively reduced disease activity in systemic lupus erythematosus patients with joint and skin manifestations, showing significant improvement in acute and subacute skin types earlier than in chronic types, while no significant benefit was observed for nonspecific skin manifestations.
research Features of the clinical course of the disease, quality of life and systemic cytokine profile in patients with chronic true eczema and depression
This study found that patients with chronic-stage true eczema and comorbid depression experienced a more severe disease progression, marked by higher inflammation levels and significantly reduced quality of life compared to those without depression.
research 504 Hair chemical use and systemic lupus erythematosus: a case-control study
The researchers in this study observed that while hair chemical use was common among females with SLE, it was not linked to the development of SLE. However, those who used chemical hair straighteners before their SLE diagnosis had a higher risk of developing cutaneous manifestations.
research A report on neglected case of systemic lupus erythematosus presenting by Degos’ skin disease and diffuse non-scarring alopecia with dramatic response to treatment
In this case report, a 38-year-old woman with Degos disease and non-scarring alopecia experienced significant hair regrowth with the current treatment protocol, highlighting its potential effectiveness in such complex conditions.
research A Neglected case of Systemic lupus erythematosus presenting by Degos’ skin disease and diffuse non-scarring alopecia with dramatic response to treatment, clinically and dermoscopy.
This case report describes a patient with systemic lupus erythematosus who developed Degos disease and non-scarring alopecia, highlighting dermoscopy's role in diagnosis and treatment prognosis.
research Alopecia areata: Time for position statement to include new systemic therapeutic advances
This paper discusses a consensus statement from European experts recommending systemic JAK inhibitors as first-line therapy for moderate to severe alopecia areata.
research A Case of Vitiligo Combined with Systemic Lupus Erythematosus Treated with Tofacitinib
In this report, a patient with vitiligo and systemic lupus erythematosus achieved complete skin repigmentation after 30 days of treatment with the oral JAK inhibitor tofacitinib, with no adverse reactions, suggesting its efficacy and safety as a potential treatment for vitiligo with coexisting autoimmune conditions.
research P44 The presentation of systemic erythematous lupus with Kikuchi-Fujimoto disease
This case report describes a 43-year-old woman diagnosed with both Kikuchi-Fujimoto disease and systemic lupus erythematosus, who showed clinical improvement after treatment with glucocorticoids and hydroxychloroquine, highlighting the rare coexistence of these conditions and the ongoing uncertainty about the precise cause of Kikuchi-Fujimoto disease.
research A rare presentation of systemic lupus erythematosus associated with thymoma-induced multiorgan autoimmunity
This study examines a diagnostic case of SLE with atypical symptoms linked to thymoma-related multiorgan autoimmunity.
research Prevalence of Systemic Hypertension and Control of Systolic Blood Pressure in a Cohort of 14 Dogs with Adrenal-Dependent Hypercortisolism during the First Year of Trilostane Treatment or after Adrenalectomy
In this study, dogs with adrenal-dependent hypercortisolism showed a decrease in the prevalence of systemic hypertension from 79% to 25% after a year of trilostane treatment or adrenalectomy, with blood pressure normalization observed by three months post-surgery in hypertensive dogs.
research Systemic lupus erythematosus presenting with homonymous hemianopia
This case report documents a rare instance where homonymous hemianopia was the first manifestation of systemic lupus erythematosus in a 42-year-old woman, suggesting its potential inclusion as an initial diagnostic indicator in SLE.
research Contemporaneous onset of systemic lupus erythematosus and severe eating disorder; neither the chicken nor the egg
This case report suggests the co-occurrence of systemic lupus erythematosus and an eating disorder in an adolescent may be linked through shared adolescent stress factors rather than neuropsychiatric lupus, despite algorithmic indications.
research Non-scarring alopecia in systemic lupus erythematosus patients at the Lagos State University Teaching Hospital: a cross-sectional study of prevalence, pattern, trichoscopy features and histopathological analysis
This study aimed to document and compare the prevalence and characteristics of hair loss in patients with systemic lupus erythematosus, noting the differences in trichoscopic and histopathologic evaluations between those with and without alopecia. Results are not reported.
research Systemic Tofacitinib Treatment in Pediatric Patients with Resistant Alopecia Areata
In this study, pediatric patients with alopecia areata treated with systemic tofacitinib showed significant improvement at 12 months, but the small sample size and retrospective design limit conclusions about its effectiveness.
research Alopecia areata after belimumab use in a patient with systemic lupus erythematosus: a paradoxical case of autoimmunity
In this case report, a woman developed severe alopecia areata approximately one year after starting belimumab for systemic lupus erythematosus, with hair loss improving upon discontinuation of the drug, suggesting a possible connection between belimumab and immune-mediated hair loss.
research Referee report. For: Case Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosus [version 2; peer review: 2 approved]
This report describes a case of digital gangrene as an early manifestation of systemic lupus erythematosus in a 56-year-old man, highlighting it as a rare complication of late-onset SLE.
research Androgenic Alopecia in a Patient with Systemic Lupus Erythematosus
In this case study, a patient with long-standing androgenic alopecia and lupus showed a satisfactory response to treatment with oral and topical minoxidil after suboptimal outcomes with previous treatments.
research An Atypical Initial Manifestation of Systemic Lupus Erythematosus: Lupus Enteritis Accompanied by Intestinal Pseudo-Obstruction and Bilateral Hydronephroureter
In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
research Systemic lupus erythematosus and diabetic mellitus is it single or two entity(es)
This case report describes a 14-year-old female patient with both Systemic Lupus Erythematosus and Diabetes Mellitus, highlighting the rarity of this combination and the importance of thorough evaluation to accurately diagnose and predict the clinical course of the disease.
research Fever and rash as initial signs of systemic autoimmune disease. Case Report.
This case report describes a 15-year-old female whose initial systemic lupus erythematosus manifestations were fever and rash appearing separately, illustrating diagnostic challenges between SLE and infection.
research Chronic Exposure with 5‐Alpha Reductase Inhibitor Ameliorates Anxiety and Depression‐like Behaviors By Reducing Systemic Oxidative Stress in D‐galactose‐Induced Aging Male Rats
In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.