Anifrolumab Treatment Improves Patient-Reported Quality of Life and Decreases Disease Activity and Corticosteroid Use in Patients with Systemic Lupus Erythematosus: A Qualitative Study in Denmark

    June 2024 in “ Lupus
    Anne Troldborg, Lauren Remkus, Daniel Eek, Bent Deleuran
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    TLDR Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.
    The study in Denmark on Anifrolumab treatment for systemic lupus erythematosus (SLE) involved 16 patients and demonstrated significant improvements in patient-reported quality of life, reduced disease activity, and decreased corticosteroid use. Patients experienced a reduction in symptoms such as fatigue, joint pain, and hair loss, with disease activity scores dropping from an average of 9 to 2 over six months. The treatment allowed 44% of patients to avoid reintroducing steroids during flares. Despite the small sample size, the study underscores the positive impact of Anifrolumab on both subjective experiences and clinical outcomes in SLE management.
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