Comparative Histopathological Analyses of Non-Scarring Alopecia in Systemic Lupus Erythematosus Patients in Lagos, Nigeria

This study examined the histopathology of non-scarring alopecia in 23 systemic lupus erythematosus (SLE) patients, comparing those with hair loss (12) to those without (11). Key findings included mucin deposition (91.7%), reduced sebaceous glands (58.3%), and epidermal atrophy (50.0%) in hair loss patients. The only significant histopathological difference between patients with and without hair loss was in the size and number of sebaceous glands. No significant differences were found between alopecic and non-alopecic scalp areas in SLE patients with hair loss.