Adherence Patterns to Medications and Their Association with Subsequent Hospitalization in Adult Egyptian Patients with Systemic Lupus Erythematosus

    August 2023 in “ Lupus
    Samar Tharwat, Elaheh Shaker
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    Studysummary In this study conducted at an Egyptian outpatient clinic, researchers found that systemic lupus erythematosus patients who were non-adherent to medication had a higher rate of hospitalization and more clinical symptoms compared to those who adhered to their prescribed treatments.
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    This study on 161 Egyptian patients with systemic lupus erythematosus (SLE) found that non-adherence to medication, assessed using the 19-item Compliance Questionnaire of Rheumatology (CQR), was significantly linked to higher hospitalization rates and more severe symptoms, such as recurrent fever, lymphadenopathy, oral ulcers, and substantial hair loss. Adherent patients, who were more likely to have frequent outpatient visits and higher antimalarial use, experienced fewer hospitalizations. Non-adherence was often due to disruptions in daily routine and fear of adverse drug reactions. The findings underscore the importance of improving medication adherence to effectively manage SLE and reduce hospitalizations.
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