115 citations
,
November 2004 in “Brain Behavior and Immunity” This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.
63 citations
,
August 2022 in “Diagnostics” This review discusses hirsutism in women with PCOS who present with normal androgen levels and highlights diagnostic challenges, reporting no new clinical findings.
60 citations
,
August 2005 in “Endocrinology” This study suggests that αMSH may play a regulatory role in human dermal papilla cells, potentially influencing immune and inflammatory responses in hair follicles, which could contribute to inflammatory alopecia.
30 citations
,
May 2019 in “Scientific Reports” This study found enhanced remyelination in the corpus callosum of late pregnant rats compared to virgin and postpartum rats, suggesting a pregnancy-associated promyelinating effect mediated, in part, by the GABA A receptor system.
24 citations
,
July 2023 in “Journal of Functional Biomaterials” This review evaluates recent advances from 2016 to 2022 in the use of microbubbles and nanobubbles, highlighting their potential for safer diagnostic and therapeutic applications in radiology and medicine without the side effects associated with traditional methods.
23 citations
,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
18 citations
,
May 2024 in “Pharmaceutics” This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.
12 citations
,
September 2020 in “Nanomaterials” This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.
11 citations
,
June 2015 in “Scientific Reports” In this study of Han Chinese women, the mitochondrial DNA N haplogroup was associated with a higher risk of late-onset systemic lupus erythematosus and its specific manifestations, such as skin impairment and neurological disturbances.
9 citations
,
August 2007 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study observed that amino acid uptake into wool follicles varies significantly, with cysteine showing the highest uptake rate, suggesting specialized transport systems that may influence wool growth.
6 citations
,
March 2024 in “Therapeutic Delivery” This review highlights novel treatment options for alopecia areata, focusing on nanoparticulate drug-delivery systems to improve the effectiveness and targeting of therapies for this complex autoimmune condition.
3 citations
,
January 2022 in “Pharmaceutics” This review examines new formulations for delivering 5-α-reductase inhibitors to improve targeted drug delivery in androgenetic alopecia, but reports no new clinical results.
2 citations
,
August 2023 in “Pharmaceutics” This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.
2 citations
,
July 2023 in “Water” In this study, the genotoxic effects of the 2020 harmful algal bloom event were linked to specific toxic algal groups affecting Tradescantia plants, making Trad-SHM and Trad-MN tests suitable for evaluating HABs' toxic potential.
2 citations
,
June 2023 in “Pharmaceutics” This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.
2 citations
,
January 2017 in “Annals of Dermatology” Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
2 citations
,
November 2011 in “InTech eBooks” This article reviews the types and characteristics of adrenal cortex tumors, including their hormone secretion and detection as incidental findings, but presents no new research results.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
May 2025 in “Journal of International Medical Research” In this study, micrografting technology was found to potentially shorten healing time compared to other grafting techniques, especially in treating burns, though results showed high heterogeneity and a risk of bias.
March 2025 in “The Egyptian Journal of Medical Microbiology” This study found that patients with diffuse hair loss had significantly higher serum levels of inflammatory cytokines IL-6 and TNF-α compared to healthy controls, suggesting a potential role of immune system activation in the pathogenesis of this condition.
June 2001 in “Proceedings of SPIE” The authors concluded that low energy laser therapy may serve as a useful complementary treatment for skin diseases such as lichen planus, infectious finger pulpits, scalp alopecia, and crural ulcers.
In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.
February 2025 in “Expert Opinion on Drug Safety” This study analyzed adverse event reports from the FDA Adverse Event Reporting System and identified new side effects of topical minoxidil, such as application site acne and cysts, which are not well-documented on product labels, suggesting a need for updated safety information.
4 citations
,
May 2009 in “Wound Repair and Regeneration” This study found that transplanting genetically modified dermal fibroblasts into full-thickness skin defects in rats led to the formation of hair follicles with mature pilosebaceous systems by 16 weeks.
July 2025 in “Pharmaceutics” This review discusses the application of transdermal drug delivery systems for androgenetic alopecia and explores new technologies to enhance drug penetration but reports no clinical results.
136 citations
,
February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
117 citations
,
September 2003 in “Molecular & cellular proteomics” This study demonstrated the development of high-density protein microarrays allowing for antibody binding characterization and serum profiling from patients with autoimmune diseases, suggesting potential for diagnostic marker discovery.
32 citations
,
December 2004 in “BMC Public Health” This study found that trained observers using the Hamilton-Norwood classification were very reliable in assessing balding patterns, while men's self-assessments were moderately accurate compared to observers.
26 citations
,
January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.
17 citations
,
July 1994 in “Journal of Dermatological Science” This article reviews the genetic and potential environmental factors in alopecia areata's pathogenesis and suggests a polygenic model but reports no new clinical findings.