research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
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research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors
Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Pharmacological Evidence for Extracts and Secondary Metabolites from Plants of the Genus Hibiscus
Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Effect of Estrogens on Skin Aging and the Potential Role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering
Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
research Hair Regrowth
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women
The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Ontogenetic Transition in Fetal Wound Transforming Growth Factor-Beta Regulation Correlates with Collagen Organization
Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
research Principles of Hair Cycle Control
Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Psoriasis Treatment in Difficult Locations: Scalp, Nails, and Intertriginous Areas
Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Androgenetic Alopecia: Clinical Features, Classification, and Treatments
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Minoxidil in Resistant Hypertension
Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.