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      Genetic Basis of Skin Appendage Development

      research Genetic basis of skin appendage development

      111 citations , January 2007 in “Seminars in cell & developmental biology”
      This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.
      Molecular Signaling in Feather Morphogenesis

      research Molecular signaling in feather morphogenesis

      85 citations , October 2006 in “Current opinion in cell biology”
      This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
      Wnt Signaling in Skin Organogenesis

      research Wnt signaling in skin organogenesis

      72 citations , April 2008 in “Organogenesis”
      This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.
      To Grow or Not to Grow: Hair Morphogenesis and Human Genetic Hair Disorders

      research To grow or not to grow: Hair morphogenesis and human genetic hair disorders

      43 citations , December 2013 in “Seminars in Cell & Developmental Biology”
      This mini-review discusses human hair follicle development and summarizes genetic disorders linked to abnormalities in hair follicle morphogenesis, structure, or regeneration, but reports no new experimental results.
      Anatomy and Function of the Skin

      research Anatomy and Function of the Skin

      40 citations , January 2016 in “Elsevier eBooks”
      This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
      Molecular and Spatial Design of Early Skin Development

      research Molecular and spatial design of early skin development

      3 citations , December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.
      How a Bird Gets Its Feathers: Insights from Chromatin Looping

      research How a Bird Gets Its Feathers: Insights from Chromatin Looping

      3 citations , June 2020 in “Developmental Cell”
      This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.
      SOX2 in the Skin: Roles in Biology and Pathology

      research SOX2 in the Skin

      1 citations , September 2015 in “Elsevier eBooks”
      This review discusses the role of Sox2 in skin development, hair follicle regeneration, cancer, and wound healing, and reports no new experimental results.
      Embryologic Layers in Dermatology: Developmental Checkpoint Disorders, Diagnostic Insight, and Regenerative Futures

      research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures

      December 2025 in “Italian Journal of Anatomy and Embryology”
      This narrative literature review examined how linking embryonic development with non-genetic skin anomalies can improve diagnostic accuracy, guide prenatal counseling, and enrich dermatology education by revealing specific vulnerabilities in skin morphogenesis and supporting advances in regenerative medicine.
      AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis

      research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis

      December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study found that AP-2α and AP-2β transcription factors are crucial for maintaining adult skin homeostasis, with their inactivation in keratinocytes leading to impaired differentiation, hair abnormalities, and inflammation, highlighting their key regulatory roles.
      Mesenchyme Governs Hair Follicle Induction

      research Mesenchyme governs hair follicle induction

      July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study found that back skin mesenchyme from mouse embryos can induce hair follicle formation even before dermal condensate formation, but R-spondin-1 alone or with a Bmp receptor inhibitor was not sufficient for hair follicle induction.
      Epithelial Stem Cells: Turning Over New Leaves

      research Epithelial Stem Cells: Turning over New Leaves

      508 citations , February 2007 in “Cell”
      This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
      Anatomy and Physiology of the Skin

      research Anatomy and Physiology of the Skin

      277 citations , July 2011 in “Journal of the Dermatology Nurses’ Association”
      The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      More Than One Way to Skin

      research More than one way to skin . . .

      218 citations , April 2008 in “Genes & Development”
      This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.
      Keratin 17 Null Mice Exhibit Age- And Strain-Dependent Alopecia

      research Keratin 17 null mice exhibit age- and strain-dependent alopecia

      122 citations , June 2002 in “Genes & Development”
      This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
      Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors

      research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors

      103 citations , October 2003 in “Birth Defects Research”
      This review discusses the multifactorial etiology of hypospadias, including genetic predispositions and possible environmental factors, and highlights the need for further studies on genetic and environmental contributions to its increasing prevalence, without presenting new findings.
      Alopecia Areata: A Comprehensive Review of Pathogenesis and Management

      research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management

      99 citations , July 2017 in “Clinical Reviews in Allergy & Immunology”
      This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
      Building Epithelial Tissues From Skin Stem Cells

      research Building Epithelial Tissues from Skin Stem Cells

      84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”
      This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.