research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
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research Screening of Microbial Strains for Fermenting Dendrobium Officinale to Enhance Polysaccharide Skin Care Effects
Fermenting Dendrobium officinale with Lactobacillus reuteri CCFM8631 increases its skin care benefits.
research Rare Cutaneous Side Effects of Imiquimod: A Review on Its Mechanisms, Diagnosis, and Management
Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.
research Folliculosebaceous Cystic Hamartoma With Spindle Cell Lipomatous And Neural Components
A woman had a unique skin growth with hair follicle, oil glands, fat cells, spindle cells, and nerve fibers.
research The Effect of Experimental Hypothyroidism on the Skin of Adult Male Albino Rats and the Therapeutic Role of Topical Triiodothyronine
Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
research The Role of Gold-Silver Nanocomposite Gel Versus Astragalus Polysaccharides on the Healing Process of Experimentally Induced Wounds in Albino Rats: A Pharmacological and Histological Comparative Study
Astragalus polysaccharides nanogel heals wounds better than Gold-Silver nanocomposite gel.
research Histological Study on the Effect of Hyaluronic Acid Injection on the Skin of Adult and Aged Albino Rats
Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.
research Opportunities for Topical Antimicrobial Therapy: Permeation of Canine Skin by Fusidic Acid
Fusidic acid can be an effective topical treatment for superficial bacterial infections in dogs.
research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research Retinoic Acid-Induced Epidermal Transdifferentiation in Skin
Retinoic acid helps change skin cells and is important for skin development and hair growth.
research Keratinocyte Stem Cells: Role in Aging
Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
research Unexpected Expression of Hemoglobin Alpha as an Endogenous Antioxidant in Epidermal Keratinocytes
Hemoglobin α acts as an antioxidant in skin cells, especially protecting hair follicle stem cells from UV damage.
research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in Mice
Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research Efficacy of Subcutaneous Injection of Platelet-Rich Plasma in Alopecia: A Clinical and Histological Pilot Study on a Rat Model with a Six-Month Long-Term Follow-Up Experience
Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Noggin Overexpression Inhibits Eyelid Opening by Altering Epidermal Apoptosis and Differentiation
Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
research Epidermal Keratinocyte Stem Cells: Their Maintenance and Regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
TCDD speeds up skin barrier formation by increasing certain gene expressions.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit During Hair Cycle
COX-2 levels change during the hair cycle and affect skin and hair growth.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.