Efficacy of Subcutaneous Injection of Platelet-Rich Plasma in Alopecia: A Clinical and Histological Pilot Study on a Rat Model with a Six-Month Long-Term Follow-Up Experience

April 2018 in “ Journal of Cosmetic Dermatology ”

Sophie Orliac, Jean Michel Serfaty, Anne Perozziello, Olivier Zurlinden, Liliane Louedec, Benjamin Dallaudière

platelet-rich plasma alopecia subcutaneous injection hair growth hair density histological improvements collagen epithelium PRP

TLDR Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.

The study conducted 5 years ago on 12 hairless rats demonstrated that subcutaneous injections of platelet-rich plasma (PRP) significantly improved hair growth and quality without causing local toxicity. The rats were divided into four quadrants and treated with PRP, platelet-poor plasma (PPP), physiological serum (PS), or no treatment. The PRP-treated quadrant showed significant hair density improvement at day 28 and month 6 compared to the PPP and PS treated quadrants. Histological improvements were also observed in the PRP treated quadrant, with increased vessels, collagen, and epithelium. The study concluded that controlled PRP might be a useful strategy to treat alopecia.

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1 / 1 results

research Efficacy of Subcutaneous Injection of Platelet-Rich Plasma in Alopecia: A Clinical and Histological Pilot Study on a Rat Model with a Six-Month Long-Term Follow-Up Experience

2 citations , April 2018 in “Journal of Cosmetic Dermatology”

Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.