Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that exosomes and secretome derived from rat hair follicle stem cells show promising potential for wound healing and tissue repair, demonstrating significant wound closure and suggesting their broader applicability in regenerative medicine.

This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.

In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.

This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.

This study found that ectodermal precursor cells derived from human induced pluripotent stem cells may enhance hair follicle morphogenesis through improved epithelial-mesenchymal interactions when cocultured with dermal cells.

This article reviews the use of the Nd:YAG laser for hair removal and reports no new research findings.

In this study, researchers developed a method to efficiently derive contractile smooth muscle cells from human hair follicle stem cells using TGF-β1 and PDGF-BB, which may advance vascular tissue engineering.

This study found that the ocular surface epithelium in mice contains distinct stem cell populations with unique cell division dynamics that change behaviorally in response to different levels of injury.

This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.

This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.

This study demonstrated that human skin can be efficiently reinnervated using human induced pluripotent stem cell-derived neural stem cells, promoting skin vitality and sensory reinnervation comparable to physiological conditions.

This review discusses recent advances in imaging techniques for monitoring stem cells in vivo and reports no new results; it suggests directions for future development in endoscopic molecular imaging tools.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This review discusses the role of heparan sulfate proteoglycans in regulating stem cell fate and highlights their potential as targets for addressing hair loss, without reporting new clinical results.

In this study, researchers found that keratinocyte-specific deletion of the autophagy mediator Atg16l1 in mice heightened skin inflammation and cancer responses, altered hair follicle stem cell activity, and sensitized keratinocytes to cell death.

This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.

Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.

This study found that the loss of ASLNC168501 accelerates hair follicle stem cell dysfunction in androgenetic alopecia through activation of the AR/miR-128-3p/IGF-1 pathway, suggesting that restoring ASLNC168501 could be a promising therapeutic strategy for hair regeneration.

This study found that the ASLNC168501 pathway has significant potential for restoring hair follicle stem cell function and promoting hair regeneration in androgenetic alopecia by counteracting the AR/miR-128-3p/IGF-1 pathway dysfunction.

This review discusses the role and regulation of quiescent adult stem cells in tissue maintenance and repair, focusing on molecular mechanisms and their implications for regenerative medicine, but reports no new clinical results.

This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

In this study, LHX2 and SOX9 were found to mark distinct epithelial progenitor cell populations within human hair follicles, suggesting roles in maintaining the hair follicle epithelium.

This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.

This study developed a technique to limit genetic recombination to regulatory T cells to investigate whether self-tolerance is maintained in non-lymphoid tissues, an area previously not well understood.

This review examines the potential of adipose-derived stem cells in disease treatment and highlights the need for further research to clarify their effectiveness and safety.

This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.

This study found that in skin blister healing, hair follicle development is compromised as stem cells repair wounds at the expense of morphogenesis gene expression.

This report suggests that TCDD may alter human epidermal stem cell populations by upregulating c-Myc, potentially leading to increased stem cell turnover during chloracne development.