Functional Endoscopy Techniques for Tracking Stem Cell Fate

The document reviewed various endoscopic imaging techniques for tracking stem cell fate, emphasizing their potential in stem cell therapies. Techniques such as fluorescence endomicroscopy, multiphoton endoscopy, and photoacoustic endoscopy were highlighted for their unique advantages in in vivo imaging with sub-cellular resolution. Gold nanoparticles were used to label stem cells for effective in vivo tracking without cytotoxicity. Despite advancements, no single modality met all criteria for comprehensive stem cell tracking, suggesting a need for integrated approaches. Multimodality imaging, combining techniques like ultrasound and optical coherence tomography, offered comprehensive insights into stem cell behavior. These methods were beneficial for tracking and monitoring implanted cells, aiming to determine the ideal therapeutic window for stem cell therapy through continuous biomarker profiling.