Strength And Tenderness: Fibronectin Joins Hair Follicle Stem Cell Niche

August 2025 in “ Journal of Investigative Dermatology ”

Richa Nayak, Yejing Ge

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research Epithelial Fibronectin Meshwork Controls Skin Regeneration

April 2025 in “Journal of Investigative Dermatology”

Fibronectin is essential for hair follicle regeneration by supporting stem cells.

research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis

23 citations , October 2021 in “Cell Stem Cell”

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis

242 citations , February 2016 in “Science”

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.