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Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Glioblastoma cells can make androgens, which might help the tumor grow.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Certain compounds found in edible mushrooms may help treat hair loss.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

A new method accurately measures nine specific hormones in human blood.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

Caizhixuan hair tonic helps treat hair loss by promoting hair growth and improving hair follicles.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Compound 4 is a promising treatment for hair loss with low toxicity.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Adding Triamcinolone to the anesthetic can reduce swelling after hair transplants, and using Platelet-Rich Plasma can improve hair thickness and patient satisfaction. The SRD5A2 gene also plays a key role in the success of hair transplants.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Personalized treatments for hair loss are becoming more effective by using genetic information.