research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
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60-90 / 1000+ results research Autophagy Protects Murine Preputial Glands Against Premature Aging and Controls Their Sebum Phospholipid and Pheromone Profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Dermatologic Manifestations of Thyroid Disease: A Literature Review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research Epidermoid Cyst of the Ear Lobule in Adults
Adult earlobe can have a benign cyst that is usually removed by surgery.
research Metallothionein Expression During Wool Follicle Development in Fetal Sheep
Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Reversible Activation of c-Myc in Skin
Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Environment of the Anagen Follicle
The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice
Mice with human skin protein K8 had more skin problems and cancer.
research Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis
DDS treatment for LABD can cause severe side effects like anemia and hair loss, requiring careful monitoring.
research Histopathological Examination of Hair Matrix Cysts
Hair matrix cysts are rare skin nodules with unique features, often needing surgical removal.
research Dermal Mass Aspirate from a Persian Cat
The Persian cat has a skin infection caused by a fungus, treatable with antifungal medication.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research A Rare Case of Multiple Keratoacanthomas Treated with Oral Acitretin and Intralesional Methotrexate
A 25-year-old man with multiple skin tumors was successfully treated with acitretin and methotrexate.
research Benign Skin Tumors: Overview, Clinical Features, Histopathology, and Treatment Options
Benign skin tumors need accurate diagnosis to ensure proper treatment.
research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating
Krt15+ cells in the mouse intestine resist radiation and can start tumors.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research Roles of Steroid Receptors in the Lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Epidermal Stem Cell Fate: What Can We Learn from Embryonic Stem Cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
research Noggin Overexpression Inhibits Eyelid Opening by Altering Epidermal Apoptosis and Differentiation
Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.