Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis

    July 2015 in “ Case Reports in Dermatology
    Eijiro Akasaka, Sato‐Jin Kayo, Hajime Nakano, Norito Ishii, Takashi Hashimoto, Daisuke Sawamura
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    Studysummary In this case study, DDS treatment for LABD was complicated by hemolytic anemia and alopecia, suggesting the need for careful monitoring of these potential side effects.
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    This document described a case of a Japanese patient with Linear IgA Bullous Dermatosis (LABD) who developed hemolytic anemia and alopecia as side effects of diaminodiphenyl sulfone (DDS) treatment. Although DDS is the first-line therapy for LABD, it can cause severe side effects, including hemolytic anemia, which can be masked by iron deficiency anemia (IDA). The patient's hair loss improved after reducing the DDS dosage, highlighting the need for careful monitoring of LABD patients on DDS to detect and manage adverse effects like hemolytic anemia and alopecia.
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