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As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

CIP/KIP proteins help stop cell division and support hair growth.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Scientists created stem cells that can grow hair and skin.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.