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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Some medicinal plants can help heal wounds and may lead to new treatments.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Finasteride helps hair growth but may cause sexual side effects.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Minoxidil promotes hair growth in male pattern baldness.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New treatments targeting specific genes show promise for treating keratin disorders.