Isotretinoin for the Treatment of Facial Lichen Planopilaris: A New Indication for an Old Drug, a Case Series Study

    August 2020 in “ Clinical case reports ”
    Farahnaz Fatemi Naeini, Fatemeh Mohaghegh, Farzaneh Danesh, Mina Saber, Parvin Rajabi
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    TLDR Isotretinoin was not effective in treating facial lichen planopilaris.
    The document discusses a case series study that explored the use of isotretinoin, a medication commonly used for severe acne, as a treatment for facial lichen planopilaris (LPP), a condition that can cause skin roughness and is related to frontal fibrosing alopecia and scalp LPP. The study found that patients with facial LPP who were treated with isotretinoin did not experience improvement in their facial papules, despite the drug's effectiveness in other skin conditions. This suggests that isotretinoin may not be a suitable treatment option for facial LPP, highlighting the need for further research to find effective treatments for this particular manifestation of the disease. The number of participants and specific results were not provided in the summary.
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