Effects of Isotretinoin on the Hair Cycle

    October 2018 in “ Journal of Cosmetic Dermatology
    Zeynep Gizem Kaya İslamoğlu, H. Cevdet Altinyazar
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    TLDR Isotretinoin at a low dose for three months does not significantly affect hair growth.
    The study, involving 30 patients with moderate-severe acne vulgaris, investigated the impact of isotretinoin on hair growth parameters. Participants received a daily dose of 0.5 mg/kg of isotretinoin and were assessed using the TrichoScan Professional program before and after 3 months of treatment. The results indicated no statistically significant changes in hair parameters, including total hair count, hair density, and the percentage of anagen and telogen hair. Consequently, the study concluded that short-term use of isotretinoin at the specified dose does not significantly alter hair growth parameters or cause alopecia. However, the study acknowledged limitations such as a small sample size and the absence of high-dose isotretinoin administration, suggesting the need for further research with more participants, higher doses, and longer-term observation.
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