Renal Tubular Dysfunction Presenting as Recurrent Hypokalemic Periodic Quadriparesis in Systemic Lupus Erythematosus

    January 2014 in “ Indian Journal of Nephrology ”
    D Prasad, Dipti Agarwal, Vinay Malhotra, Pankaj Beniwal
    TLDR A woman with lupus had muscle weakness due to kidney issues and was successfully treated with medication.
    A 30-year-old woman with systemic lupus erythematosus (SLE) presented with recurrent hypokalemic periodic quadriparesis and symptoms including joint pain, oral ulcers, photosensitivity, and hair loss. She was diagnosed with distal renal tubular acidosis (dRTA) and successfully treated with oral potassium chloride, sodium bicarbonate, hydroxychloroquine, and a short course of steroids. This case highlighted the importance of assessing tubular dysfunction in SLE patients, as renal involvement in SLE is typically glomerulonephritis, making isolated tubular dysfunction a rare but significant finding.
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