January 2007 in “Edward Elgar eBooks” In this study, overexpressing TSPO in the mouse hippocampal dentate gyrus led to significant anxiolytic and antidepressant-like effects, partly through increased allopregnanolone biosynthesis.
In this experimental study, mixing temperature and rate were found to significantly influence cream's physical properties, with mixing rate affecting spreadability and temperature affecting viscosity.
128 citations
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December 2006 in “Journal of Biological Chemistry” This study found that overexpression of the enzyme spermidine/spermine N1-acetyltransferase in mice was associated with increased fat oxidation and a leaner phenotype, while knock-out mice exhibited increased fat accumulation.
8 citations
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November 2019 in “Journal of Trace Elements in Medicine and Biology” Higher hair iron levels are linked to changes in brain structure and function.
7 citations
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June 2012 in “Journal of dairy science” This study found that topical application of bovine milk polar lipids accelerated hair cycle progression in mice, showing potential for use in cosmetic products.
4 citations
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November 2021 in “Journal of Cosmetic Dermatology” The researchers reported that QR678 Neo® combined with intralesional steroids significantly improved hair regrowth and patient satisfaction in treating alopecia areata compared to steroids alone.
2 citations
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November 2017 in “Histochemistry and Cell Biology” This study observed varying levels of polyamines in different compartments of rat hair follicles, indicating their potential involvement in hair growth, especially in the matrix and inner root sheath layers.
February 2024 in “Indian Dermatology Online Journal” In this study, researchers at a tertiary care center reported a significant correlation between severe COVID-19 cases and the presence of androgenic alopecia, suggesting that androgen receptor expression may influence COVID-19 severity.
3 citations
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January 2019 in “Therapeutic advances in urology” This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.
May 2023 in “Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy” This study developed a synchronized fluorescence spectroscopic approach to quantify finasteride and tadalafil in various forms, achieving high accuracy with %recoveries of about 99.62% and 100.19% respectively, and demonstrated superior environmental friendliness compared to previous methods.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
39 citations
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November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
18 citations
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June 2016 in “Brain Research” Increasing TSPO in the brain may help improve memory problems.
14 citations
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January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
14 citations
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November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
3 citations
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April 2016 in “Research and reports in urology” In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
205 citations
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September 2018 in “Nutrients” This review summarizes the volatile components, biological activities, and potential safety concerns of essential oils from various Curcuma species, but reports no new clinical results.
188 citations
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December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
103 citations
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April 2010 in “Journal of Investigative Dermatology” This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.
91 citations
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July 2004 in “Journal of Biological Chemistry” This study found that overexpression of the enzyme SSAT in a mouse model significantly reduced prostate tumor size and progression, suggesting it could be a promising strategy against prostate cancer.
61 citations
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April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
57 citations
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May 2021 in “Molecules” This review explores the chemical composition and biological activities of essential oils from selected aromatic roots, highlighting their potential for various industries, though more research is needed to standardize their bioactive components.
47 citations
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February 2019 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the chemical composition and traditional medicinal uses of Eruca sativa, particularly its potential applications in topical preparations for hair growth and treating skin infections, but reports no new clinical results.
36 citations
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April 2022 in “Nutrients” This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.
35 citations
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January 2022 in “Frontiers in Neurology” This review utilizes clinical vignettes to detail various pain syndromes associated with multiple sclerosis, including their pathophysiology and management strategies, highlighting conditions like central neuropathic pain, Lhermitte's phenomenon, and trigeminal neuralgia as they relate to different lesion types.
24 citations
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August 2022 in “Immunity” This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.
24 citations
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December 2018 in “Inflammation and Regeneration” This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.
24 citations
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June 2015 in “Journal of Investigative Dermatology” This study observed that epidermal-specific deletion of aPKCλ in mice disrupts hair follicle stem cell quiescence, leading to altered hair follicle cycling and skin anomalies.
22 citations
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April 2020 in “Frontiers in Cellular and Infection Microbiology” This study found significant differences in scalp microbiome composition and volatile organic metabolites between individuals with alopecia areata and healthy controls, suggesting potential microbiome-related therapeutic interventions for hair growth disorders.
17 citations
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May 2022 in “Frontiers in Immunology” This review explores recent advances in inflammation resolution and considers how macrophage reprogramming might help address severe COVID-19 outcomes, particularly those involving cytokine storms, but it reports no new experimental results.