research Case Report: Heterozygous Mutation in HTRA1 Causing Typical Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.
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450-480 / 1000+ resultsresearch The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
research Cushing's Syndrome Complicating Pemphigoid Gestationis
Careful management of steroid use is crucial in pregnant women with bullous pemphigoid to avoid complications like Cushing syndrome.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Finasteride Delays Atherosclerosis Progression in Mice and Is Associated With a Reduction in Plasma Cholesterol in Men
Finasteride may lower cholesterol and slow heart disease progression.
research Astragalus Membranaceus and Cinnamomum Cassia Stimulate Hair Follicle Differentiation-Related Growth Factor via Wnt/Beta-Catenin Pathway
The YH complex, made from Astragalus membranaceus and Cinnamomum cassia, may help treat hair loss by promoting hair growth and follicle development.
research Cell-Free Fat Extract Restores Hair Loss: A Novel Therapeutic Strategy for Androgenetic Alopecia
A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
research Medicinal and Edible Plant Allium Macrostemon Bunge for the Treatment of Testosterone-Induced Androgenetic Alopecia in Mice
The wild garlic plant, Allium macrostemon Bunge, can promote hair growth and could potentially be used to treat hair loss.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Neuropathic Pruritus: An Underrecognized and Often Misdiagnosed and Difficult to Treat Medical Condition
Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.
research Mechanical Force Drives the Initial Mesenchymal-Epithelial Interaction During Skin Organoid Development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Role of the Soluble Epoxide Hydrolase in Hair Follicle Stem Cell Homeostasis and Hair Growth
The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.
research Skin Manifestations of Rheumatological Diseases
Different rheumatological diseases can cause specific skin problems.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
research Antiepileptogenic Effects of Trilostane in the Kainic Acid Model of Temporal Lobe Epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.
research Effects of Guasha on Histomorphology of Scraped Skin and Expression of Calcitonin Gene-Related Peptide and Substance P in Rats
Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.
research Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments
Hair proteins have weak spots in their α-helical segments.
research Queries and Minor Notes
Washing can prevent cancer from lubricating oils, extreme body temperatures need more study, Sulfomid is not recognized, no reliable diphtheria carrier treatment except surgery, eyelid injuries should heal before repair, heterophile antibody test is specific for mononucleosis, chlorine inhalations for colds are outdated, and wheat germ is safe.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research The Pathogenesis of Alopecia Areata in Rodent Models
Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
research Anesthetics and Platelets
The document suggests that hair loss after stopping birth control may be similar to post-pregnancy hair loss and could recur with future pregnancies.
research Cutaneous Complications of Chemotherapeutic Agents
Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
research Skin Biopsy
Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.
research Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution
Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
research Mouse Models for the Study of Human Hair Loss
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
research Eyelash Trichomegaly: Review of Congenital, Acquired, and Drug-Associated Etiologies for Elongation of the Eyelashes
The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Lymphomatoid Granulomatosis: Case Study and Treatment
Early diagnosis and aggressive treatment are crucial for better outcomes in lymphomatoid granulomatosis.