3 citations
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December 2024 in “International Journal of Dermatology” This review examined the psychological effects, mechanisms, health associations, and treatments related to premature hair graying, highlighting factors like genetics, oxidative stress, smoking, and diet, with the aim of enhancing understanding and addressing its broader implications.
3 citations
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December 2023 in “Cell proliferation” This review suggests that the umbilical cord-derived mesenchymal stem cell secretome presents a promising approach for skin regeneration and wound healing due to its multiple therapeutic properties, highlighting its potential over traditional treatments for conditions like chronic wounds and alopecia.
2 citations
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June 2025 in “Cosmetics” This study observed that a five-week topical treatment with cold-pressed Rosa canina seed oil significantly reduced mean wrinkle scores and UV-induced spots in volunteers, suggesting potential anti-aging and photoprotective benefits attributed to its high carotenoid content.
1 citations
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July 2025 in “BMC Medicine” The authors concluded that establishing and standardizing methods for data collection are crucial to improving PCOS diagnosis and research due to challenges observed in data harmonization across diverse international cohorts.
June 2026 in “Bulletin of Mathematical Biology” This study reported that in male subjects with androgenetic alopecia, there is greater uncertainty in hair growth duration, with regulatory factors in the dermal papilla significantly affecting outcomes.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review summarizes current clinical evidence on platelet-rich plasma, highlighting its effectiveness in treating androgenetic alopecia and as an adjunctive therapy for acne scars, while noting challenges in standardizing preparation techniques.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
August 2025 in “Annals of Medicine” This review discusses recent advances in using extracellular vesicles as a potential treatment for alopecia and highlights ongoing challenges in their clinical application and mass production; no new clinical results are reported.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” This systematic review found that both cellular and acellular stem cell-based therapies are safe and able to improve hair regeneration and density in patients with androgenic alopecia, although some results may be temporary.
387 citations
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May 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.
40 citations
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June 2021 in “Clinical, cosmetic and investigational dermatology” This review explores the efficacy and outcomes of using JAK inhibitors for treating alopecia areata, noting advancements in understanding the disease's pathomechanisms and suggesting that JAK inhibitors may offer targeted therapeutic benefits by blocking specific inflammatory pathways involved in this chronic condition.
8 citations
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March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
6 citations
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January 2021 in “Journal of the American Academy of Dermatology” This review discusses the use of platelet-rich plasma for alopecia treatment and notes a lack of data on the consistency of FDA-approved PRP devices in clinical settings.
4 citations
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January 2015 in “Indian Journal of Dermatology” This study reports that severe androgenic alopecia prevalence in young Caucasian men increases with age, varies by region, and that body mass index may be a risk factor.
August 2026 in “Journal of Clinical Medicine” In this study, researchers found that the management of alopecia areata in Poland is inadequate, despite following international guidelines, due to limited access to advanced treatments and insufficient use of severity assessments and psychosocial support.
January 2026 in “Skin Health and Disease” This study conducted a survey among consultant dermatologists in Ireland to explore their use of JAK inhibitors for treating alopecia areata, acknowledging challenges posed by the lack of global guidelines and long-term safety data.
106 citations
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August 2021 in “Pharmaceuticals” This review discusses the role of extracellular vesicles in wound healing and explores their potential applications in skin repair and treatment of dermal diseases, reporting no new clinical findings.
48 citations
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December 2022 in “Biomolecules” This review discusses recent advancements in 3D bioprinting for skin regeneration and describes potential improvements for clinical applications, but it reports no new experimental results.
40 citations
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July 2024 in “Bioengineering” This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.
37 citations
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November 2019 in “Journal of Microbiology and Biotechnology” This study found that loliolide enhanced hair growth-related functions in 3D dermal papilla spheroids by activating AKT/β-catenin signaling pathways, with increased expression of related growth factors and genes.
27 citations
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February 2023 in “Oxidative Medicine and Cellular Longevity” This study found that platelet-derived mitochondria can promote wound healing by reducing oxidative stress-induced apoptosis in vascular endothelial cells, with survivin identified as a potential target.
26 citations
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March 2020 in “Antioxidants” This study found that microwave-assisted Opuntia humifusa extract improved antioxidant and anti-inflammatory properties to counteract particulate matter's harmful effects on HaCaT keratinocytes.
25 citations
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August 2015 in “Molecules” This study found that mimosine dipeptide enantiomers inhibit melanogenesis and cyclooxygenase enzymes in B16F10 melanoma cells, suggesting potential for treating skin hyperpigmentation and inflammation.
14 citations
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July 2015 in “International Journal of Molecular Sciences” This study found that S-Methylmethionine sulfonium (SMMS) enhances cell survival and reduces damage from UVB irradiation in skin cells, suggesting its potential as a cosmetic ingredient for UV protection.
13 citations
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January 2024 in “Journal of Nanobiotechnology” This research reported that a newly developed adhesive wound dressing (SIS/PAA/LAP) demonstrated higher tissue adhesion and burst strength compared to conventional products, and improved tissue repair outcomes in animal models, suggesting potential for enhanced wound healing applications.
10 citations
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October 2019 in “Iranian Biomedical Journal” This study found that a 5 µM concentration of simvastatin significantly increased the differentiation of hair follicle stem cells into keratinocytes in vitro.
7 citations
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December 2023 in “International Journal of Molecular Sciences” This study demonstrated that Forsythiaside A protected against oxidative stress in both cell models and a mouse model of liver damage, suggesting its potential as a liver-protective agent.
7 citations
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August 2023 in “Frontiers in Cardiovascular Medicine” This review discusses recent preclinical strategies for enhancing mesenchymal stem cell delivery to ischemic cardiac and peripheral tissues but reports no clinical results.
7 citations
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August 2020 in “Plastic and reconstructive surgery. Global open” In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.