Extracellular Vesicles in Skin Wound Healing

    August 2021 in “ Pharmaceuticals ”
    Deimantė Narauskaitė, Gabrielė Vydmantaitė, Justina Rusteikaitė, Revathi Sampath, Akvilė Rudaitytė, Gabija Stašytė, María Isabel Aparicio Calvente, Aistė Jekabsone
    TLDR Extracellular vesicles help heal skin wounds and could be used for better treatments.
    The document reviewed the role of extracellular vesicles (EVs) in skin wound healing, highlighting their involvement in all four phases of the healing process: hemostasis, inflammation, proliferation, and remodeling. It discussed the potential of EVs as therapeutic interventions for non-healing wounds, abnormal scarring, and infections, emphasizing their natural wound healing capabilities and the possibility of engineering them for specific pharmaceutical purposes. The review aimed to enhance scientific understanding of EVs in skin repair and explored recent findings in their application for wound healing, skin regeneration, and treatment of dermal diseases, including the use of stem cell-derived, plant-derived, and engineered EVs.
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