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Microscopic delivery system that sends growth-promoting signals to hair follicles
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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Research
5 / 1000+ resultsresearch Development of Hairless Laboratory Guinea Pigs: The Biological Studies
Hairless guinea pigs are useful for research in allergies, skin tests, and diseases.
research Extracellular Vesicles in Skin Wound Healing
Extracellular vesicles help heal skin wounds and could be used for better treatments.
research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research JAK Inhibitors in the Therapy of Comorbid Diseases: Atopic Dermatitis and Alopecia Areata - Literature Review and Clinical Practice Experience
JAK inhibitors effectively treat severe atopic dermatitis and alopecia areata.
research Do Nanoparticles Have a Future in Dermal Drug Delivery?
Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
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5 / 1000+ resultscommunity Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
community Hair loss research is a money grab
Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.
community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits
Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.
community I think I’ve finally found the reason for my hair loss
The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.