research T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts
T cells affect skin cell genes in inflammatory diseases, and therapy can normalize these changes.
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5 / 1000+ resultsresearch 190 A cross-sectional study evaluating skin, hair, nail and bone disease in patients with focal dermal hypoplasia
Patients with Focal Dermal Hypoplasia often experience skin, nail, hair, and bone issues, and may benefit from calcium and vitamin D supplements.
research Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases
This study suggests that human DSCCs may aid in hair follicle regeneration and reduce microinflammation, with potential applications in regenerative medicine evaluated through a new morphometric analysis.
research FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES
This study confirms that finasteride inhibits the conversion of testosterone to dihydrotestosterone in human dermal fibroblasts, suggesting potential therapeutic use for androgen-related skin disorders.
research 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction
This study demonstrated that hiPSC-derived hair-bearing skin organoids lacked sufficient type VII collagen at the epidermal-dermal junction, indicating a need for further maturation to model certain forms of epidermolysis bullosa effectively.
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5 / 1000+ resultscommunity Why is my dermatologist strictly against derma stamping/derma rolling?
Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.
community 17M - beat the norwood reaper in 4 months. Am I a hyper responder? Can I maintain for a year until I can start fin?
A 17-year-old improved his hairline using minoxidil and derma stamping, planning to start finasteride at 18. He received advice on dosing and potential side effects to maintain results.
community Don't be inconsistent with Minoxidil, you will lose progress fast. My new plan for future.
Inconsistent minoxidil use led to hair loss, prompting a plan to resume consistent application with derma stamping, red light therapy, and DHT blockers like clascoterone or RU58841. The user avoids finasteride and dutasteride due to past side effects.
community Is this growth? Should i keep doing this?
The user has been using Minoxidil, vitamins, and a derma roller for 2.5 months with some regrowth observed. They are hesitant to add finasteride or dutasteride due to potential side effects, considering topical finasteride as a safer option.
community My experience with finasteride and outlook on hairloss
The user started finasteride at 21.5 years old and saw significant improvement in hair volume and maintenance of the hairline, though some recession continued. They are optimistic about future hair loss treatments like CRISPR and are not currently using additional treatments like minoxidil or derma-rolling.
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5 / 801 resultslearn Exosomes
Microscopic delivery system that sends growth-promoting signals to hair follicles
learn Vascular Endothelial Growth Factor
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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