Trichodysplasia spinulosa can occur after a heart transplant due to immunosuppressive drugs.
49 citations
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March 2014 in “Journal of Investigative Dermatology” This study demonstrated that combining AMD3100 with low-dose tacrolimus in a stem cell mobilization approach significantly reduced wound healing time and improved scar and hair follicle regeneration in full-thickness skin wounds.
February 2025 in “Archives of Dermatological Research” Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
July 2024 in “Journal of Investigative Dermatology” This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.
September 2025 in “British Journal of Hospital Medicine” This study found that certain plasma protein ratios, specifically AGRN/HSPG2 and DECR1/FKBP1B, were significantly associated with an increased risk of alopecia areata, indicating potential causal relationships but reverse causality was not supported.
January 2025 in “Nutrients” In this study, researchers found that specific genetic variations at loci rs1160312, rs6113491, and rs1041668 are independent risk factors for androgenetic alopecia in men, and these risks can be influenced by diet.
May 2006 in “Hair transplant forum international” This abstract provides a brief case overview from 2002 regarding a female patient with Sjogren's disease; it reports no new research findings.
May 2009 in “Hair transplant forum international” This article reviews online discussions on managing psoriasis in patients considering hair restoration surgery, and it reports no new clinical findings.
June 2026 in “Drug Delivery and Translational Research” This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.
May 2026 in “Frontiers in Medicine” This study describes a patient with Rothmund–Thomson syndrome-like symptoms who displayed hair improvement after combination therapy, despite carrying an ANAPC1 gene variant of uncertain significance.
53 citations
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May 2010 in “PubMed” This paper discusses spironolactone as a potential off-label treatment for female pattern hair loss, noting its ability to halt hair loss progression and induce partial regrowth in a significant number of women but reports no new clinical results.
372 citations
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December 2004 in “Nature Genetics”
July 2024 in “Clinical Cosmetic and Investigational Dermatology” Certain immune cells are linked to non-scarring hair loss, suggesting potential for immune-targeted treatments.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper documents a case of natural reversal of moderate-to-severe androgenetic alopecia without medical intervention, but emphasizes it is an individual observation not generalizable to broader populations.
1 citations
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July 2018 in “Journal of Pakistan Association of Dermatology” This randomized prospective study found that microneedling combined with autologous platelet-rich plasma resulted in significant hair regrowth and reduction in SALT score after 12 weeks in patients with chronic and stable alopecia areata, suggesting it as a safe and efficient treatment option.
11 citations
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June 2005 in “Stem Cells and Development” This study demonstrated that stem cells from the small intestine can differentiate into skin cells and reduce skin damage in irradiated mice, supporting the theory of stem cell plasticity.
More research is needed to confirm PRP's effectiveness for scarring alopecia.
October 2021 in “Dermatology reports” The care model improved timely diagnosis and treatment for psoriasis and psoriatic arthritis.
11 citations
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July 2008 in “Facial Plastic Surgery Clinics of North America” This article discusses the benefits of follicular unit transplantation for male hair restoration, highlighting its ability to achieve natural-looking results with minimal recovery time and low risk of complications, and reports no new clinical results.
April 2016 in “Journal of Investigative Dermatology” This study found that disrupting Sdf1-Cxcr4 signaling promoted tissue regeneration in wild-type mice, hinting at potential strategies to induce such regeneration in mammals.
8 citations
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January 2018 in “Journal of the American Academy of Dermatology” This study found that maintenance treatment with diphenylcyclopropenone was associated with a lower relapse rate in alopecia areata patients, highlighting the importance of adjusting treatment intervals post-improvement.
June 2026 in “Journal of Cosmetic Dermatology” PDRN may help with female hair loss, but more research is needed.
April 2026 in “Human Genome Variation” This study identified a specific hemizygous intronic variant in the MBTPS2 gene associated with IFAP syndrome in a patient, revealing exon skipping and reduced normal transcript expression through long-read RNA sequencing.
July 2024 in “Medical alphabet” This study found that the SBN system effectively evaluates and describes the severity and clinical variant of alopecia areata using a standardized scale, aiding in patient management and disease course prediction.
32 citations
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August 2016 in “Science Signaling” This study developed PiSCES biosignatures that distinguished alopecia areata patients from controls, revealing enhanced basal TCR signaling and a potential disease-specific signaling network signature.
2 citations
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April 2024 in “Advanced Materials” This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.
January 2025 in “Fìzìologìčnij žurnal” This study found that in patients with elevated fibrinogen levels undergoing revision rhinoplasty, PDRN decreased M1 cytokines and increased M2 cytokines, potentially offering a new therapeutic approach, but further research is needed to understand its mechanisms and effects fully.
April 2019 in “Journal of Investigative Dermatology” This study reported that mSKPs and DMSCs share similarities in biological characteristics but exhibit distinct transcriptome profiles, with mSKPs being more immune-related and DMSCs more associated with differentiation and disease pathways.
In this study, researchers aim to evaluate the effectiveness and safety of combining plum-blossom needle tapping with ginger juice rubbing to prevent hair loss in obese women after metabolic bariatric surgery, through a randomized controlled trial involving 96 participants.
September 2023 in “Journal of the Dermatology Nurses’ Association” This case study reports that platelet-rich plasma treatment led to total hair regrowth in a 71-year-old woman with alopecia areata who had not responded to previous standard therapies.