A Documented Case of Stage-Level Natural Reversal of Advanced Androgenetic Alopecia

December 2025 in “ Zenodo (CERN European Organization for Nuclear Research) ”

WU, JEFFI CHAO HUI

androgenetic alopecia Norwood–Hamilton classification vertex density hair shaft thickness pigmentation AGA

TLDR A person's severe hair loss naturally reversed without treatment.

The document is a detailed case study of a natural reversal of moderate-to-severe androgenetic alopecia (AGA) at stage 3V of the Norwood–Hamilton classification, observed without pharmacological or medical interventions. It records changes in vertex density, coverage area, hair shaft thickness, and pigmentation. This personal case record is not intended as clinical validation or a population-level conclusion but serves as a primary source for hair loss research and exploring natural recovery possibilities, with further analyses to be discussed in future works.

View this study on zenodo.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 20M don’t know where to start or where to buy

in General 404 upvotes 2 months ago

A 20-year-old is experiencing hair thinning and seeks advice on starting treatment and regrowing hair. They are considering using Minoxidil, finasteride, or RU58841.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 104 upvotes 3 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 27 upvotes 3 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.