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    Glossary SMAD proteins

    proteins that transmit signals from cell surface to nucleus

    SMAD proteins are a group of molecules that play a crucial role in transmitting signals from the cell surface to the nucleus. They are involved in the TGF-beta signaling pathway, which regulates various cellular processes such as growth, differentiation, and apoptosis. Essentially, they act as messengers that help cells respond to external signals, ensuring proper cellular function and development.

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    Research 30 of 793

    1. Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway Evidence-based Complementary and Alternative Medicine · 2013 · 18 citations
    2. Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients 2023
    3. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    4. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    5. Preliminary study on microR-148a and microR-10a in dermal papilla cells of Hu sheep BMC Genetics · 2019 · 28 citations
    6. Stem Cells and their Niches Journal of Investigative Dermatology · 2013 · 1 citations
    7. BMP signaling in the control of skin development and hair follicle growth Differentiation · 2004 · 165 citations
    8. MON-203 Dermatological Effects Of Hormone Replacement Therapy Journal of the Endocrine Society · 2025
    9. Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury Endocrinology · 2012 · 56 citations
    10. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    11. Epimorphic regeneration in mice is p53-independent Cell Cycle · 2010 · 20 citations
    12. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    13. ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway Cell Death Discovery · 2022 · 18 citations
    14. 4-<i>O</i>-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling Biomolecules & Therapeutics · 2017 · 5 citations
    15. Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity Developmental Biology · 2008 · 28 citations
    16. A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle bioRxiv (Cold Spring Harbor Laboratory) · 2017
    17. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations
    18. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    19. Kaempferol enhances hair growth by regulating JAK3/STAT6 and TGF-β/Smad signaling in human dermal papilla cells and a C57BL/6 mousemodel Records of Natural Products · 2025
    20. Human bone marrow mesenchymal stem cells-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway Research Square (Research Square) · 2020
    21. Injectable platelet-rich fibrin promotes proliferation and trichogenic inductivityof dermal papilla cells through activating TGF-β/Smad signaling pathway Cellular and Molecular Biology · 2024 · 4 citations
    22. Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface ˜The œAmerican journal of pathology · 2008 · 41 citations
    23. Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model Biological & Pharmaceutical Bulletin · 2014 · 22 citations
    24. Salicylate induces epithelial actin reorganization via activation of the AMP-activated protein kinase and promotes wound healing and contraction in mice Scientific Reports · 2024 · 8 citations
    25. Hair follicle development and related gene and protein expression of skins in Rex rabbits during the first 8 weeks of life Asian-Australasian Journal of Animal Sciences · 2018 · 14 citations
    26. Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Research · 2002 · 79 citations
    27. A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle Journal of Molecular Cell Biology · 2018 · 26 citations
    28. IMMUNOHISTOCHEMICAL EXPRESSION OF KERATIN PROTEINS IN KERATOACANTHOMAS OF THE SKIN Oncology Reports · 1994 · 2 citations
    29. Regulation of stem cell function by protein ubiquitylation EMBO Reports · 2014 · 55 citations
    30. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations