research Smad7-Induced β-Catenin Degradation Alters Epidermal Appendage Development
This study found that Smad7 perturbs hair follicle development while promoting sebaceous gland formation by antagonizing Wnt/β-catenin signaling in transgenic mice.
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5 / 1000+ results research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
In this study, human bone marrow mesenchymal stem cell-derived exosomes significantly accelerated cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.
research Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
This study found that overexpression of Smad7 in transgenic mice led to severe alterations in multiple epithelial tissues, resulting in early death after birth.
research Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes
This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.
research The 800-nm diode laser irradiation induces skin collagen synthesis by stimulating TGF-β/Smad signaling pathway
This study concluded that the 800-nm diode laser is effective in enhancing skin structure and collagen expression via the TGF-β/Smad pathway, suggesting potential for non-ablative rejuvenation.
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