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The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.

Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.

Vitamin D receptor helps control hair growth genes in skin cells.

β-Catenin is essential for new hair growth after skin injury.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.

BMP signaling is essential for the development of touch domes.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Mice without collagen VI have slower hair growth normally but faster regrowth after injury.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.