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Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Endocannabinoids help control mast cell activity in human skin.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Skin problems are very common in people with end-stage kidney disease.

Wnt signaling is crucial for skin wound healing and reducing scars.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Fat from the body can help improve hair growth and scars when used in skin treatments.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.