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Topical immunotherapy for alopecia areata may work by creating immune cell clusters in the skin.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Eating peptides from certain shellfish may help wounds heal faster by reducing inflammation.

m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.

Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.

Retinol may affect immune responses in people with frequent skin boils.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Tofacitinib helps improve skin conditions in people with Down syndrome, especially alopecia areata.

Exosomes show promise for treating skin diseases and improving skin regeneration.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.

Only 40 nm nanoparticles can enter skin cells effectively for potential vaccine delivery.

Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Different oil products cause varying levels of skin irritation in mice, which could potentially lead to tumors.

NIPP1 is important for healthy skin and could help treat skin inflammation.

Grasp protein helps maintain skin health after UVB exposure.

Laser hair removal can be effective for darker skin but requires careful use to avoid side effects.

Sunlight simulation causes skin inflammation, with different skin types reacting at different levels of exposure.

Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.

Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.

Bacteria can help skin regenerate through a process called IL-1β signaling.

Differences in skin and gut bacteria may contribute to alopecia areata.

Researchers found a new way to isolate sweat glands from the scalp for study and culture.

New materials and methods could improve skin healing and reduce scarring.