Elucidating the Role of the Skin and Gut Microbiome in the Development and Pathogenesis of Alopecia Areata

The study investigated the role of the skin and gut microbiome in alopecia areata (AA) by comparing 25 AA patients to 25 healthy controls. Significant differences in microbiome composition were found between the two groups. The findings suggested that dysbiosis in the microbiome might contribute to systemic inflammation and autoimmune alopecia, providing a basis for future research on disease severity, prognosis, dietary practices, and therapeutic responses.