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    Glossary Skin Penetration

    process by which substances pass through the outer skin layer

    Skin penetration refers to the process by which substances pass through the outermost layer of the skin, known as the stratum corneum, to reach deeper layers. This is a critical concept in dermatology and pharmacology, as it influences the effectiveness of topical medications and skincare products. Factors such as molecular size, solubility, and the condition of the skin can affect how well a substance penetrates.

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    Research 30 of 1000+

    1. Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer Scientific Reports · 2021 · 34 citations
    2. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies Skin pharmacology and physiology · 2018 · 35 citations
    3. Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers Pharmaceutical Research · 2020 · 5 citations
    4. Enhanced skin penetration of lidocaine through encapsulation into nanoethosomes and nanostructured lipid carriers: a comparative study ˜Die œPharmazie · 2016 · 15 citations
    5. Novel iron oxide nanocarriers loading finasteride or dutasteride: Enhanced skin penetration for topical treatment of alopecia International Journal of Pharmaceutics · 2020 · 12 citations
    6. Development and Skin Penetration Pathway Evaluation Using Confocal Laser Scanning Microscopy of Microemulsions for Dermal Delivery Enhancement of Finasteride Pharmaceutics · 2022 · 1 citations
    7. Enhanced skin penetration of Finasteride loaded DMSO-liposomes for the treatment of androgenic alopecia: comparison with conventional liposomes Drug Development and Industrial Pharmacy · 2023 · 1 citations
    8. Correction to: Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers Pharmaceutical Research · 2020
    9. Lipid-based nanocarriers coupled with CO 2 laser-mediated drug delivery enhance skin penetration and hair follicle targeting Journal of drug targeting · 2026
    10. Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations AAPS PharmSciTech · 2024 · 29 citations
    11. Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers Journal of Investigative Dermatology · 1989 · 3 citations
    12. Preclinical and Clinical Development of a Penetration Enhancer SEPA 0009 CRC Press eBooks · 2005
    13. Penetration of drugs through skin, a complex rate-controlling membrane 2012 · 211 citations
    14. Invasomes: Vesicles for Enhanced Skin Delivery of Drugs Springer eBooks · 2016 · 6 citations
    15. Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:<i>in vitro</i>evaluation of drug permeation by infrared spectroscopy Pharmaceutical Development and Technology · 2012 · 26 citations
    16. Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia Pharmaceuticals · 2023 · 5 citations
    17. Penetration of silver nanoparticles into porcine skin<i>ex vivo</i>using fluorescence lifetime imaging microscopy, Raman microscopy, and surface-enhanced Raman scattering microscopy Journal of Biomedical Optics · 2014 · 90 citations
    18. The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin Journal of Controlled Release · 2016 · 9 citations
    19. Heat Enhanced Follicular Delivery of Isotretinoin to the Skin Pharmaceutical research · 2019 · 8 citations
    20. Microneedle-Assisted Penetration of Fibronectin Nanogels for Enhanced Anti-Aging Healthcare and Diabetic Wound Healing ACS Nano Medicine · 2026
    21. Advance and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System Pharmaceutics · 2023 · 2 citations
    22. Targeted skin delivery of topically applied drugs by optimised formulation design 2016 · 2 citations
    23. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction European Journal of Pharmaceutics and Biopharmaceutics · 2012 · 21 citations
    24. Enhancement of percutaneous absorption of Finasteride by cosolvents, cosurfactant and surfactants Pharmaceutical Development and Technology · 2009 · 24 citations
    25. Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety Phytochemistry Reviews · 2023 · 1 citations
    26. The Role of Labrasol® in the Enhancement of the Cutaneous Bioavailability of Minoxidil in Phospholipid Vesicles 2012
    27. Formulation and Characterization of Transethosomes for Enhanced Transdermal Delivery of Propranolol Hydrochloride Micro and Nanosystems · 2020 · 11 citations
    28. Latanoprost-Loaded Nanotransfersomes Designed for Scalp Administration Enhance Keratinocytes Proliferation Molecular Pharmaceutics · 2022
    29. Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator Biomaterials Research · 2022 · 17 citations
    30. Skin Penetration of Caffeine and Cafestol using Liposomes: Exploring the Benefits of a Combined Delivery System AAPS PharmSciTech · 2026