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    Glossary Penetration

    ability of a substance to pass through skin or hair

    Penetration, in the context of hair and scalp treatments, refers to the ability of a substance to pass through the outer layer of the skin or hair shaft to reach deeper layers. This is crucial for the effectiveness of topical treatments, such as minoxidil for hair growth, as it ensures that active ingredients can reach the hair follicles where they exert their effects.

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    Research 10 of 1000+

    1. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles 2004 · 316 citations
    2. Penetration of drugs through skin, a complex rate-controlling membrane 2012 · 211 citations
    3. Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil International Journal of Pharmaceutics · 2009 · 128 citations
    4. Penetration and storage of particles in human skin: Perspectives and safety aspects European Journal of Pharmaceutics and Biopharmaceutics · 2011 · 122 citations
    5. Penetration of silver nanoparticles into porcine skin<i>ex vivo</i>using fluorescence lifetime imaging microscopy, Raman microscopy, and surface-enhanced Raman scattering microscopy Journal of Biomedical Optics · 2014 · 90 citations
    6. Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle Journal of controlled release · 2002 · 54 citations
    7. Penetration and Local Effect of Vitamin A on the Skin of the Guinea Pig., Experimental Biology and Medicine · 1954 · 45 citations
    8. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies Skin pharmacology and physiology · 2018 · 35 citations
    9. Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion Journal of Pharmaceutical Sciences · 1995 · 33 citations
    10. Lipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies International Journal of Nanomedicine · 2014 · 28 citations
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    Community 9 of 11

    1. So I earlier used to use the alchol variant but it lead to dryness in scalp and I switched to a non alchol variant that contains oleanolic acid , is it more or less the same , coz I heard alchol helps in better penetration so wondering if this would reduce my hair growth. Reddit · 22 Mar 2023
    2. Propylene glycol vs ethyl alcohol(70% or 96%) for topical finasteride solution. Pros and cons? Reddit · 22 Apr 2024
    3. Am I losing my transplant results by using only topical finasteride as opposed to oral? Reddit · 1 Sept 2026
    4. What’s a good carrier for GHK-Cu or AHK-Cu peptides to penetrate skin? Reddit · 27 Apr 2026
    5. Nanoxidil Is Probably Better Than Minoxidil. Big Pharma Is Why You’ve Never Heard Of It. Reddit · 22 Mar 2026
    6. Topical dutasteride significantly outperforms oral finasteride Reddit · 22 Sept 2025
    7. Can microneedling damage existing hair? Reddit · 20 Aug 2025
    8. Can use olive oil instead of PG (propylene glycol) or glycerin in topical finasteride preparation? Reddit · 11 Aug 2024
    9. 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2 Reddit · 29 Jul 2024
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