16 citations,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
11 citations,
January 2013 in “Veterinary dermatology” Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
140 citations,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
101 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
99 citations,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
40 citations,
December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
39 citations,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
21 citations,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
14 citations,
June 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
9 citations,
August 2017 in “Photochemistry and Photobiology” Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
9 citations,
March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
6 citations,
January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
4 citations,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
4 citations,
June 2021 in “Dermatology” Scientists created a 3D skin model to study a chronic skin disease and test treatments.
2 citations,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
2 citations,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
2 citations,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
2 citations,
September 2014 in “The American Journal of Cosmetic Surgery” Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
1 citations,
January 2019 in “Elsevier eBooks” New scaffold materials help heal severe skin wounds and improve skin regeneration.
1 citations,
January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
Regenerative cosmetics can improve skin and hair by reducing wrinkles, healing wounds, and promoting hair growth.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.