154 citations,
October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
39 citations,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Fatp4 is crucial for healthy skin development and function.
36 citations,
October 1996 in “Dermatologic Clinics” Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
10 citations,
November 2017 in “Skin Appendage Disorders” Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.
8 citations,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
1 citations,
January 2024 in “Microorganisms” Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
January 2024 in “Advanced Science” New microspheres help heal skin wounds and regrow hair without scarring.
September 2023 in “Nature Communications” Immune cells are essential for skin regeneration using biomaterial scaffolds.
68 citations,
March 2018 in “Biomaterials” Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.
854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
9 citations,
January 2015 in “Fundamental & clinical pharmacology” Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
22 citations,
June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
6 citations,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
38 citations,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
3 citations,
June 2021 in “PLOS ONE” A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
10 citations,
May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
47 citations,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
10 citations,
January 2016 in “Elsevier eBooks” Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
3 citations,
July 2008 in “British journal of dermatology/British journal of dermatology, Supplement” Terbinafine can cause hair loss.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.