September 2018 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” In this study, FN-based fiber scaffolds designed using Rotary Jet-Spinning were shown to enhance wound healing and reduce scar formation in a mouse model, suggesting potential for regenerating healthy skin structure.
June 2026 in “ACS Nano Medicine” This study designed fibronectin nanogel microneedles, reporting their potential to enhance tissue repair by improving collagen organization, reducing inflammation, and promoting angiogenesis in both photoaged and diabetic wound models.
This study introduced fibronectin nanogel microneedles (FNG MNs) that demonstrated improved tissue penetration and transdermal delivery, restoring skin homeostasis in a photoaged mouse model and enhancing collagen deposition and angiogenesis in a diabetic wound rat model.
355 citations
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August 2013 in “Acta Biomaterialia” This study found that a nanoparticle-in-nanofiber system significantly accelerated wound healing in rats by promoting angiogenesis and tissue regeneration more effectively than a commercial wound dressing.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
